Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572647 | 0.85 | ALDH1A1 (0.39) | NPC1RAB9ASMN1; SMN2TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL6571006 | 0.83 | ALDH1A1 (0.38) | NPC1RAB9ASMN1; SMN2TDP1MEN1 | |
| SCHEMBL6573470 | 0.83 | DPP4 (0.47) | BACE1NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL6011299 | 0.81 | ALDH1A1 (0.39) | NPC1RAB9ASMN1; SMN2TDP1MEN1 | |
| SCHEMBL6576009 | 0.81 | PRKCI (0.46) | BACE1NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL28271668 | 0.80 | CA12 (0.44) | NPC1RAB9ASMN1; SMN2TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL6782393 | 0.80 | ACHE (0.47) | BACE1NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL6573481 | 0.78 | PDE10A (0.52) | NPC1RAB9ASMN1; SMN2TDP1MEN1 | |
| SCHEMBL146272 | 0.76 | PRKCI (0.55) | BACE1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL30880219 | 0.75 | PDE10A (0.64) | NPC1RAB9ASMN1; SMN2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| EP-1208077-A1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-05-29 | — | — | EP | disclosed |
| WO-2002002507-A1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-01-10 | — | — | WO | disclosed |