SCHEMBL6576009

SCHEMBL6576009

CCc1ccccc1-c1cc(N)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.46
PDE10A Q9Y233 1/20 0.46
ACHE P22303 1/20 0.45
ALDH1A1 P00352 5/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
TP53 P04637 2/20 0.43
CYP3A4 P08684 2/20 0.43
CSNK2A2 P19784 1/20 0.43
CSNK2B P67870 1/20 0.43
CSNK2A1 P68400 1/20 0.43
CSNK2A3 Q8NEV1 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
KDM4E B2RXH2 4/20 0.42
ALOX15 P16050 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6782393 0.98 ACHE (0.47) PRKCIPDE10AACHEALDH1A1NPC1
SCHEMBL6573470 0.84 DPP4 (0.47) PRKCIPDE10AACHEALDH1A1NPC1
SCHEMBL9006036 0.84 PTPRC (0.60) ALDH1A1NPC1RAB9ASMN1; SMN2TDP1
SCHEMBL8926002 0.82 ANPEP (0.47) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1
SCHEMBL6570988 0.82 ALDH1A1 (0.46) ALDH1A1NPC1RAB9ASMN1; SMN2TDP1
SCHEMBL6575809 0.81 BACE1 (0.41) PRKCIPDE10AACHEALDH1A1NPC1
SCHEMBL15026755 0.81 MAPT (0.53) ALDH1A1NPC1RAB9ASMN1; SMN2CSNK2A2
Hydrochloric Acid SCHEMBL6571889 0.81 ALDH1A1 (0.44) ACHEALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL8406692 0.79 ALOX15 (0.44) ALDH1A1SMN1; SMN2TP53CSNK2A2CSNK2B
SCHEMBL980892 0.79 GABRA1 (0.50) ALDH1A1CSNK2A2CSNK2BCSNK2A1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3544076-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2019-09-25 EP disclosed
EP-1208077-B1 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS WELLA AG (DE) 2004-04-21 EP disclosed
EP-1208077-A1 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS Wella Aktiengesellschaft (DE) 2002-05-29 EP disclosed
WO-2002002507-A1 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2002-01-10 WO disclosed