Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28021551 | 0.85 | ACHE (0.50) | ACHETSHRCASP1PDE10AALDH1A1 | |
| SCHEMBL4640070 | 0.83 | CYP3A4 (0.50) | TSHRCASP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL25588908 | 0.78 | ADRB2 (0.41) | ALDH1A1CYP3A4ALOX12HIF1AKDM4E | |
| SCHEMBL16932995 | 0.77 | PTK2 (0.37) | ALDH1A1ALOX12HIF1AGAAHTT | |
| SCHEMBL3077884 | 0.74 | ALDH1A1 (0.50) | TSHRCASP1PDE10AALDH1A1CYP3A4 | |
| SCHEMBL456953 | 0.72 | CYP3A4 (0.60) | TSHRCASP1PDE10AALDH1A1CYP3A4 | |
| SCHEMBL19307999 | 0.72 | ALDH1A1 (0.48) | TSHRCASP1PDE10AALDH1A1CYP3A4 | |
| SCHEMBL29752049 | 0.72 | CYP3A4 (0.60) | TSHRCASP1PDE10AALDH1A1CYP3A4 | |
| SCHEMBL1536776 | 0.69 | ACHE (0.50) | ACHEALDH1A1CYP3A4MAPK1ALOX12 | |
| SCHEMBL30213582 | 0.69 | LMNA (0.65) | ACHEALDH1A1CYP3A4MAPK1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920853-B1 | Hair dye compositions | P & G CLAIROL INC (US) | 2004-01-21 | — | — | EP | disclosed |
| EP-0920853-A1 | Hair dye compositions | Bristol-Myers Squibb Company (US) | 1999-06-09 | — | — | EP | disclosed |