Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | CDC7 | O00311 | 6/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501969 | 0.88 | PTGS2 (0.62) | PTGS2CDC7DBF4MAPK14ALOX5 | |
| SCHEMBL6505966 | 0.86 | PTGS2 (0.50) | PTGS2CDC7DBF4MAPK14ALOX5 | |
| SCHEMBL6286370 | 0.81 | MEN1 (0.50) | PTGS2CDC7DBF4MAPK14ALOX5 | |
| SCHEMBL6286367 | 0.80 | PTGS2 (0.48) | PTGS2CDC7DBF4MAPK14ALOX5 | |
| SCHEMBL15690382 | 0.79 | PTGS2 (0.50) | PTGS2CDC7DBF4MAPK14ALOX5 | |
| SCHEMBL6600796 | 0.78 | PTGS2 (0.49) | PTGS2CDC7DBF4MAPK14ALOX5 | |
| SCHEMBL6503233 | 0.77 | PTGS2 (0.78) | PTGS2MAPK14 | |
| SCHEMBL6279375 | 0.77 | PTGS2 (0.54) | PTGS2CDC7DBF4MAPK14CCNE1 | |
| SCHEMBL6280962 | 0.77 | PTGS2 (0.48) | PTGS2CDC7DBF4MAPK14ALOX5 | |
| SCHEMBL6502554 | 0.77 | PTGS2 (0.51) | PTGS2CDC7DBF4MAPK14ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097555-A1 | Concomitant drugs | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097555-A1 | Concomitant drugs | TNF, CHUK, CNKSR1 | PTGS2 109/4885CDC7 1288/4885DBF4 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.