Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420369 | 0.72 | — | — | |
| SCHEMBL6574546 | 0.71 | — | — | |
| SCHEMBL6850656 | 0.69 | CRHBP (0.34) | CRHBPCRHR2ALDH1A1TDP1 | |
| Bromide SCHEMBL6846809 | 0.68 | CRHBP (0.33) | CRHBPCRHR2 | |
| SCHEMBL10586210 | 0.66 | CES2 (0.38) | ALDH1A1TDP1POLBMAPK1 | |
| SCHEMBL10714023 | 0.62 | NPSR1 (0.40) | ALDH1A1TDP1MAPK1 | |
| SCHEMBL5314132 | 0.60 | — | — | |
| SCHEMBL7224951 | 0.60 | ALDH1A1 (0.33) | CRHBPCRHR2ALDH1A1TDP1 | |
| Biphenyl SCHEMBL6919136 | 0.59 | ALDH1A1 (0.53) | CRHBPCRHR2ALDH1A1TDP1POLB | |
| Biphenyl SCHEMBL27821216 | 0.59 | CRHBP (0.56) | CRHBPCRHR2ALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |