Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576344 | 1.00 | CYP1A2 (0.44) | CYP1A2HPGDGRIK1TSHRMMP1 | |
| SCHEMBL6209557 | 0.84 | CYP1A2 (0.61) | CYP1A2CPA3 | |
| SCHEMBL6169492 | 0.84 | CYP1A2 (0.61) | CYP1A2CPA3 | |
| SCHEMBL5695683 | 0.83 | SLC6A3 (0.47) | CYP1A2GRIK1TSHRMEN1HTT | |
| SCHEMBL5695679 | 0.83 | SLC6A3 (0.47) | CYP1A2GRIK1TSHRMEN1HTT | |
| SCHEMBL9814713 | 0.83 | CPA3 (0.54) | CYP1A2TSHRCPA3 | |
| SCHEMBL6294971 | 0.83 | CPB2 (0.50) | CYP1A2GRIK1TSHRLAP3ERAP2 | |
| SCHEMBL1857365 | 0.79 | CYP1A2 (0.61) | CYP1A2GRIK1LAP3ERAP2ERAP1 | |
| SCHEMBL5695682 | 0.79 | TSHR (0.46) | CYP1A2TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5695680 | 0.79 | TSHR (0.46) | CYP1A2TSHRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870762-B1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-5872281-A | COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0870762-A1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |