SCHEMBL657644

SCHEMBL657644

Sc1nc(-c2ccccc2)n[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 8/20 0.61
NR1H3 Q13133 7/20 0.61
NPC1 O15118 6/20 0.50
RAB9A P51151 6/20 0.50
LMNA P02545 2/20 0.50
HPGDS O60760 1/20 0.50
DGAT1 O75907 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.49
HPGD P15428 2/20 0.49
TP53 P04637 1/20 0.49
CYP1A2 P05177 1/20 0.49
ALPL P05186 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
ADORA2A P29274 1/20 0.49
S1PR1 P21453 1/20 0.45
S1PR3 Q99500 1/20 0.45
MEN1 O00255 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4865340 0.81 JAK2 (0.49) LMNAMAPT
SCHEMBL7200528 0.79 NR1H2 (0.56) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL4873033 0.79 SMN1; SMN2 (0.63) LMNASMN1; SMN2HPGDTP53CYP1A2
SCHEMBL11401007 0.77 CYP1A2 (0.59) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL9526164 0.77 PDGFRB (0.49) NPC1RAB9AHPGDSCYP1A2MAPT
SCHEMBL666693 0.76 NR1H2 (1.00) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL2485799 0.75 XDH (0.49) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL17574086 0.74 NR1H2 (0.96) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL1686718 0.74 NR1H2 (0.61) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL1436121 0.74 NR1H2 (0.61) NR1H2NR1H3NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108598196-B High-weather-resistance solar cell back plate and preparation method thereof 山东冬瑞高新技术开发有限公司 2020-03-27 CN claimed
CN-108598196-A A kind of high-weatherability solar cell backboard and preparation method thereof 山东冬瑞高新技术开发有限公司 2018-09-28 CN claimed
CN-108530872-A A kind of cucurbit urea groups fire resistant flame retardant CABLE MATERIALS and preparation method thereof 山东冬瑞高新技术开发有限公司 2018-09-14 CN claimed
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP claimed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US claimed
CN-108598196-B High-weather-resistance solar cell back plate and preparation method thereof 山东冬瑞高新技术开发有限公司 2020-03-27 CN disclosed
CN-108598196-A A kind of high-weatherability solar cell backboard and preparation method thereof 山东冬瑞高新技术开发有限公司 2018-09-28 CN disclosed
CN-108530872-A A kind of cucurbit urea groups fire resistant flame retardant CABLE MATERIALS and preparation method thereof 山东冬瑞高新技术开发有限公司 2018-09-14 CN disclosed
US-20180009213-A1 LITHOGRAPHIC PRINTING PLATES PRECURSORS COMPRISING A RADIATION SENSITIVE IMAGEABLE LAYER WITH A CROSSLINKED SURFACE MYLAN GROUP (VN) 2018-01-11 US disclosed
US-20170190168-A1 LITHOGRAPHIC PRINTING PLATES PRECURSORS COMPRISING A RADIATION SENSITIVE IMAGEABLE LAYER WITH A CROSSLINKED SURFACE MYLAN GROUP (VN) 2017-07-06 US disclosed
CN-106459760-A Lithographic printing plates precursors comprising a radiation sensitive imageable layer with a crosslinked surface 米兰集团 2017-02-22 CN disclosed
CN-104111584-A Photosensitive resin composition ASAHI KASEI E MATERIALS CORP 2014-10-22 CN disclosed
EP-0542763-A1 POST-PROCESSING STABILIZATION OF PHOTOTHERMOGRAPHIC EMULSIONS. MINNESOTA MINING & MFG (US) 1993-05-26 EP disclosed
US-5196301-A 3-substituted-5-alkylthio-1,2,4-triazoles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-23 US disclosed
WO-1992002853-A1 POST-PROCESSING STABILIZATION OF PHOTOTHERMOGRAPHIC EMULSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-02-20 WO disclosed
US-4542094-A HYDROXYTETRAZAINDENES AND MERCAPTO-NITROGENCONTAINING HETEROCYLIC COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-17 US disclosed
EP-0107488-A2 Silver halide emulsions KONICA CORPORATION (JP) 1984-05-02 EP disclosed
US-4254259-A HERBICIDES INDIANA UNIVERSITY FOUNDATION (US) 1981-03-03 US disclosed
US-3985739-A 3-Heterocyclic thiomethylcephalosporins SMITHKLINE CORPORATION (US) 1976-10-12 US disclosed
US-3968226-A 3-Heterocyclic thiomethylcephalosporins as antibacterial agents SMITHKLINE CORPORATION (US) 1976-07-06 US disclosed