Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579051 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2RIPK1 | |
| SCHEMBL6576487 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2RIPK1 | |
| SCHEMBL3920174 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2RIPK1 | |
| SCHEMBL3920170 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2RIPK1 | |
| SCHEMBL7859393 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2RIPK1 | |
| SCHEMBL30949073 | 0.81 | AOC3 (0.48) | LMNASMN1; SMN2CYP3A4AOC3HTR1A | |
| SCHEMBL8322574 | 0.81 | CHRNA7 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2RIPK1 | |
| SCHEMBL30949064 | 0.81 | AOC3 (0.48) | LMNASMN1; SMN2CYP3A4AOC3HTR1A | |
| SCHEMBL4386877 | 0.81 | TAAR1 (0.54) | ALDH1A1MAPTLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL11799471 | 0.81 | CYP19A1 (0.47) | ALDH1A1LMNASMN1; SMN2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118222538-B | Halohydrin dehalogenase mutant and application thereof | 南京工业大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-118222538-A | Halohydrin dehalogenase mutant and application thereof | 南京工业大学 | 2024-06-21 | — | — | CN | disclosed |
| US-6743939-B2 | NITRIC OXIDE SYNTHASE INHIBITORS; SUCH AS 4-CHLORO-2-(((1)-4-(METHYLAMINO)-1-PHENYLBUTYL)OXY)BENZONITRILE | ASTRAZENECA AB (SE) | 2004-06-01 | — | — | US | disclosed |
| EP-1263714-B1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-04-28 | — | — | EP | disclosed |
| US-20030105161-A1 | Novel phenylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2003-06-05 | — | — | US | disclosed |
| EP-1263714-A1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062713-A1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105161-A1 | Novel phenylheteroalkylamine derivatives | NOS1, CYP1A1, NOS2 | ALDH1A1 450/4885MAPT 4461/4885LMNA 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.