Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066863 | 0.86 | TAAR1 (0.62) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL30949064 | 0.83 | AOC3 (0.48) | HIF1ATSHRNFKB1TDP1ALOX15 | |
| SCHEMBL30949073 | 0.83 | AOC3 (0.48) | HIF1ATSHRNFKB1TDP1ALOX15 | |
| SCHEMBL9772731 | 0.81 | IGF1R (0.41) | — | |
| SCHEMBL6578930 | 0.81 | AOC3 (0.47) | TSHRNFKB1KDM4EALOX15CYP2C9 | |
| SCHEMBL6579051 | 0.81 | ALDH1A1 (0.40) | TAAR1HIF1ATDP1KDM4ECYP2C9 | |
| SCHEMBL6576494 | 0.81 | ALDH1A1 (0.40) | TAAR1HIF1ATDP1KDM4ECYP2C9 | |
| SCHEMBL6577385 | 0.81 | AOC3 (0.47) | TSHRNFKB1KDM4EALOX15CYP2C9 | |
| SCHEMBL6577383 | 0.81 | AOC3 (0.47) | TSHRNFKB1KDM4EALOX15CYP2C9 | |
| SCHEMBL6576487 | 0.81 | ALDH1A1 (0.40) | TAAR1HIF1ATDP1KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533804-A | CD47 antibodies and methods of use thereof | 印希彼有限公司 | 2020-08-14 | — | — | CN | disclosed |
| US-9950032-B2 | Compositions and methods for lung regeneration | AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) | 2018-04-24 | — | — | US | disclosed |
| WO-2018057703-A1 | EphA5- AND GRP78 BINDING ANTIBODIES AND USES THEREOF AND SELECTION OF PHAGE-DISPLAYED ACCESSIBLE RECOMBINANT TARGETED ANTIBODIES | STC.UNM (US) | 2018-03-29 | — | — | WO | disclosed |
| US-20150125490-A1 | COMPOSITIONS AND METHODS FOR LUNG REGENERATION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) | 2015-05-07 | — | — | US | disclosed |
| US-7629380-B2 | Antitumor agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-12-08 | — | — | US | disclosed |
| US-20070286872-A1 | Live Attenuated Nidovirus Vaccines | VANDERBILT UNIVERSITY (US) | 2007-12-13 | — | — | US | disclosed |
| US-20070219174-A1 | METHODS OF TREATING CANCER USING HYPOFRACTIONATED RADIATION AND TEXAPHYRINS | PHARMACYCLICS, INC. (US) | 2007-09-20 | — | — | US | disclosed |
| US-20070072790-A1 | Antitumor agents | AF CHEMICALS | 2007-03-29 | — | — | US | disclosed |
| US-6855549-B1 | Methods and compositions for increasing the infectivity of gene transfer vectors | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219174-A1 | METHODS OF TREATING CANCER USING HYPOFRACTIONATED RADIATION AND TEXAPHYRINS | TEX10, TEX13A, DIS3 | TAAR1 2665/4885HIF1A 465/4885HTR3A 2486/4885 |
| US-20150125490-A1 | COMPOSITIONS AND METHODS FOR LUNG REGENERATION | CD68, BMP4, S100B | TAAR1 3947/4885HIF1A 178/4885HTR3A 4716/4885 |
| US-20070072790-A1 | Antitumor agents | RB1, TP53, FOXM1 | TAAR1 2147/4885HIF1A 773/4885HTR3A 4462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.