Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 1.00 |
| ▸ | MAOA | P21397 | 4/20 | 1.00 |
| ▸ | F3 | P13726 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | XDH | P47989 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | P4HB | P07237 | 1/20 | 0.75 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.72 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.72 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.72 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.72 |
| ▸ | BCHE | P06276 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987387 | 1.00 | MAOB (1.00) | MAOBMAOAF3MAPTXDH | |
| SCHEMBL8987383 | 1.00 | MAOB (1.00) | MAOBMAOAF3MAPTXDH | |
| SCHEMBL657702 | 1.00 | MAOB (1.00) | MAOBMAOAF3MAPTXDH | |
| Hydrochloric Acid SCHEMBL11823312 | 0.98 | MAOB (0.97) | MAOBMAOAF3MAPTXDH | |
| Hydrochloric Acid SCHEMBL11823315 | 0.98 | MAOB (0.97) | MAOBMAOAF3MAPTXDH | |
| 4,4'-Dimethoxychalcone SCHEMBL978243 | 0.92 | F3 (1.00) | MAOBMAOAF3MAPTXDH | |
| 4,4'-Dimethoxychalcone SCHEMBL978242 | 0.92 | F3 (1.00) | MAOBMAOAF3MAPTXDH | |
| 4',4-Dichlorochalcone SCHEMBL659211 | 0.87 | MAOB (0.86) | MAOBMAOAF3MAPTCYP1B1 | |
| 4',4-Dichlorochalcone SCHEMBL659210 | 0.87 | MAOB (0.86) | MAOBMAOAF3MAPTCYP1B1 | |
| SCHEMBL25189143 | 0.86 | MAPT (1.00) | MAOBMAOAF3MAPTXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290427-B2 | Anti-invasive compounds | UNIVERSITEIT GENT (BE) | 2016-03-22 | — | — | US | claimed |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-08 | — | — | US | claimed |
| EP-2810198-A1 | ANTI-INVASIVE COMPOUNDS | Universiteit Gent (BE) | 2014-12-10 | — | — | EP | claimed |
| WO-2013113722-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2013-08-08 | — | — | WO | claimed |
| US-20250051299-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | DAIKIN INDUSTRIES, LTD. (JP) | 2025-02-13 | — | — | US | disclosed |
| US-12162854-B2 | Production method for fluoromethyl derivative | DAIKIN INDUSTRIES, LTD. (JP) | 2024-12-10 | — | — | US | disclosed |
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |
| CN-113429280-B | Method for preparing chalcone compounds by selective hydrogenation reduction of alkynone under catalysis of Ti (III) complex | 陕西师范大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-113429280-A | Method for preparing chalcone compounds by selective hydrogenation reduction of alkynone under catalysis of Ti (III) complex | 陕西师范大学 | 2021-09-24 | — | — | CN | disclosed |
| US-20210206740-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | DAIKIN INDUSTRIES, LTD. (JP) | 2021-07-08 | — | — | US | disclosed |
| EP-3792240-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | Daikin Industries, Ltd. (JP) | 2021-03-17 | — | — | EP | disclosed |
| EP-2961743-B1 | 1-SUBSTITUTED, 4-(SUBSTITUTED PHENOXYMETHYL)-1,2,3-TRIAZOLE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND METHODS FOR PREPARATION THEREOF | FDC LTD (IN) | 2018-06-20 | — | — | EP | disclosed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-0731796-B1 | 1,3,5-TRISUBSTITUTED PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-08-02 | — | — | EP | disclosed |
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |
| EP-0540604-A1 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Aventis Pharma S.A. (FR) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001675-A2 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206740-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | AFF1, AFF2, ROS1 | MAOB 20/4885MAOA 17/4885F3 122/4885 |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | MMP3, MMP10, MIF | MAOB 4150/4885MAOA 4248/4885F3 610/4885 |
| US-12162854-B2 | Production method for fluoromethyl derivative | AFF1, AFF2, ROS1 | MAOB 20/4885MAOA 17/4885F3 122/4885 |
| US-20250051299-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | AFF1, AFF2, ROS1 | MAOB 20/4885MAOA 17/4885F3 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.