Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262401 | 0.82 | PYGL (0.57) | PYGLPLAULTB4RPPARATTR | |
| SCHEMBL6577513 | 0.80 | PYGL (0.68) | PYGLPLAULTB4RPPARAMEN1 | |
| SCHEMBL9780857 | 0.75 | KMT2A (0.61) | PYGLLTB4RPPARAALDH1A1MAPT | |
| SCHEMBL9780778 | 0.73 | KMT2A (0.62) | PYGLLTB4RPPARAMEN1HPGD | |
| SCHEMBL23752503 | 0.72 | PYGL (1.00) | PYGLPLAULTB4RPPARAMEN1 | |
| SCHEMBL7262405 | 0.72 | PYGL (1.00) | PYGLPLAULTB4RPPARAMEN1 | |
| SCHEMBL6575170 | 0.72 | PYGL (0.51) | PYGLPLAULTB4RALDH1A1LMNA | |
| Sebacic Acid SCHEMBL448447 | 0.72 | HDAC3 (0.61) | PPARAALDH1A1LMNAGAAMAPT | |
| SCHEMBL27815831 | 0.72 | HDAC3 (0.61) | PPARAALDH1A1LMNAGAAMAPT | |
| Octanedioate SCHEMBL27794753 | 0.72 | HDAC3 (0.61) | PPARAALDH1A1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294682-B1 | ACYLPHENYL UREA DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF AS A MEDICAMENT | AVENTIS PHARMA GMBH (DE) | 2004-04-28 | — | — | EP | disclosed |
| EP-1294682-A1 | ACYLPHENYL UREA DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF AS A MEDICAMENT | Aventis Pharma Deutschland GmbH (DE) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001094300-A1 | ACYLPHENYL UREA DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF AS A MEDICAMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-12-13 | — | — | WO | disclosed |