Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752503 | 0.81 | PYGL (1.00) | PYGLPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL7262405 | 0.81 | PYGL (1.00) | PYGLPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL6577510 | 0.80 | PYGL (0.57) | PYGLPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL9780857 | 0.77 | KMT2A (0.61) | PYGLALDH1A1KMT2AHPGDMAPT | |
| SCHEMBL7262401 | 0.75 | PYGL (0.57) | PYGLPOLBPLAULTB4RPPARA | |
| SCHEMBL9780778 | 0.75 | KMT2A (0.62) | PYGLMEN1KMT2AHPGDLTB4R | |
| SCHEMBL12857780 | 0.74 | POLB (0.64) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8073029 | 0.74 | PYGL (0.47) | PYGLPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL14088967 | 0.72 | POLB (0.69) | POLBALDH1A1RAB9ALMNAHPGD | |
| SCHEMBL6575170 | 0.71 | PYGL (0.51) | PYGLALDH1A1RAB9ALMNAPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294682-B1 | ACYLPHENYL UREA DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF AS A MEDICAMENT | AVENTIS PHARMA GMBH (DE) | 2004-04-28 | — | — | EP | disclosed |
| EP-1294682-A1 | ACYLPHENYL UREA DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF AS A MEDICAMENT | Aventis Pharma Deutschland GmbH (DE) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001094300-A1 | ACYLPHENYL UREA DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF AS A MEDICAMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-12-13 | — | — | WO | disclosed |