Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658601 | 0.90 | PDPK1 (0.41) | L3MBTL1MMP1KMT2AMEN1POLB | |
| SCHEMBL659012 | 0.88 | GLA (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL657352 | 0.88 | PDPK1 (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL656363 | 0.85 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1 | |
| SCHEMBL657976 | 0.82 | PDPK1 (0.49) | L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL656175 | 0.81 | KMT2A (0.47) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL657877 | 0.80 | CYP2C9 (0.50) | L3MBTL1ALDH1A1KMT2ANPC1POLB | |
| SCHEMBL658836 | 0.79 | UTS2R (0.39) | L3MBTL1ALDH1A1KMT2APOLB | |
| SCHEMBL657803 | 0.77 | PDPK1 (0.47) | SRD5A2ERCC5FEN1L3MBTL1MMP1 | |
| SCHEMBL7109215 | 0.72 | NPC1 (0.52) | L3MBTL1ALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | claimed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | SRD5A2 4627/4885ERCC5 3532/4885FEN1 3610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.