Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578529 | 0.79 | ALDH1A1 (0.56) | NPC1PIN1TSHRALDH1A1LMNA | |
| SCHEMBL5916381 | 0.74 | LMNA (0.44) | KMT2AMEN1POLBL3MBTL1ATM | |
| SCHEMBL7109704 | 0.72 | KMT2A (0.50) | NPC1KMT2AMEN1NPSR1POLB | |
| SCHEMBL6250715 | 0.72 | KMT2A (0.69) | NPC1KMT2AMEN1NPSR1POLB | |
| SCHEMBL658601 | 0.72 | PDPK1 (0.41) | KMT2AMEN1POLBL3MBTL1MAPT | |
| SCHEMBL12767662 | 0.71 | KMT2A (0.53) | NPC1KMT2AMEN1NPSR1POLB | |
| SCHEMBL8111908 | 0.71 | CASP1 (0.48) | KMT2AMEN1PIN1TSHRALDH1A1 | |
| SCHEMBL7109210 | 0.71 | KMT2A (0.67) | NPC1KMT2AMEN1NPSR1POLB | |
| SCHEMBL27774182 | 0.70 | MMP8 (0.44) | KMT2ANPSR1POLBPIN1TSHR | |
| SCHEMBL16616993 | 0.70 | KMT2A (0.60) | NPC1KMT2AMEN1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352687-A1 | Preparation of new layered double hydroxides exchanged with diisopropylamide for c-c bond forming reaction | Council of Scientific and Industrial Research (IN) | 2003-10-15 | — | — | EP | disclosed |