Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 4/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 3/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.39 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580216 | 0.88 | CTSK (0.50) | CTSKCACNA1BFUCA1 | |
| SCHEMBL6581006 | 0.87 | SIGMAR1 (0.43) | CTSKCACNA1BALDH1A1 | |
| SCHEMBL6580277 | 0.83 | ALDH1A1 (0.45) | CTSKCACNA1BALDH1A1KMT2ACASP3 | |
| SCHEMBL6580369 | 0.82 | CTSK (0.44) | CTSKCACNA1BCASP3CAPN1CASP1 | |
| SCHEMBL6582315 | 0.82 | CTSK (0.51) | CTSK | |
| Hydrochloric Acid SCHEMBL27483445 | 0.79 | CTSK (0.47) | CTSKCACNA1BFUCA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6580455 | 0.79 | CTSK (0.47) | CTSKCACNA1BFUCA1ALDH1A1 | |
| SCHEMBL6580809 | 0.78 | CTSK (0.58) | CTSKUTS2RCAPN1 | |
| SCHEMBL6578107 | 0.78 | UTS2R (0.52) | CTSKUTS2RCASP3CAPN1CASP1 | |
| SCHEMBL6578118 | 0.78 | CTSK (0.51) | CTSKUTS2RCASP3CAPN1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |