Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578074 | 0.87 | CTSK (0.49) | CTSKCACNA1BALDH1A1 | |
| SCHEMBL6583959 | 0.86 | CTSK (0.52) | CTSK | |
| SCHEMBL6582309 | 0.85 | CTSK (0.44) | SIGMAR1CTSK | |
| SCHEMBL6580216 | 0.80 | CTSK (0.50) | CTSKCACNA1B | |
| SCHEMBL6580369 | 0.79 | CTSK (0.44) | SIGMAR1CTSKCACNA1B | |
| SCHEMBL6580277 | 0.77 | ALDH1A1 (0.45) | CTSKCACNA1BALDH1A1SMN1; SMN2 | |
| SCHEMBL6580403 | 0.74 | CTSK (0.57) | CTSK | |
| SCHEMBL6578303 | 0.73 | CTSK (0.65) | CTSK | |
| Hydrochloric Acid SCHEMBL27483445 | 0.72 | CTSK (0.47) | CTSKCACNA1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL6580455 | 0.72 | CTSK (0.47) | CTSKCACNA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |