Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.51 |
| ▸ | MMP9 | P14780 | 7/20 | 0.51 |
| ▸ | MMP8 | P22894 | 5/20 | 0.51 |
| ▸ | MMP3 | P08254 | 12/20 | 0.49 |
| ▸ | MMP1 | P03956 | 8/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580390 | 0.83 | MMP2 (0.51) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL6578119 | 0.81 | MMP2 (0.56) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL6578655 | 0.79 | MMP2 (0.53) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL6575904 | 0.77 | MMP1 (0.55) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL6578667 | 0.76 | STS (0.51) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL6578081 | 0.74 | MMP2 (0.48) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL7079165 | 0.73 | MMP2 (0.54) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL5196301 | 0.70 | HDAC3 (0.63) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL3266605 | 0.70 | MMP2 (0.54) | MMP2MMP3MMP1 | |
| SCHEMBL6578098 | 0.70 | MMP2 (0.51) | MMP2MMP9MMP8MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968182-B1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES HAVING MMP AND TNF INHIBITORY ACTIVITY | DARWIN DISCOVERY LTD (GB) | 2004-05-06 | — | — | EP | claimed |