Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654684 | 0.84 | AKR1A1 (0.53) | AKR1A1AKR1B1 | |
| SCHEMBL4706329 | 0.83 | AKR1A1 (0.55) | AKR1A1AKR1B1 | |
| SCHEMBL8657565 | 0.81 | AKR1A1 (0.56) | AKR1A1AKR1B1 | |
| SCHEMBL4177715 | 0.80 | AKR1A1 (0.51) | AKR1A1AKR1B1 | |
| SCHEMBL6629050 | 0.80 | AKR1A1 (0.44) | AKR1A1AKR1B1 | |
| Hydrochloric Acid SCHEMBL4173571 | 0.80 | AKR1A1 (0.50) | AKR1A1AKR1B1 | |
| SCHEMBL8660288 | 0.79 | AKR1A1 (0.62) | AKR1A1AKR1B1 | |
| SCHEMBL13814328 | 0.79 | AKR1A1 (0.47) | AKR1A1AKR1B1 | |
| SCHEMBL8657562 | 0.79 | AKR1A1 (0.54) | AKR1A1AKR1B1 | |
| SCHEMBL8396211 | 0.78 | AKR1B1 (0.47) | AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135124-B1 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUDED INDOLEALKANOIC ACIDS | INST FOR PHARM DISCOVERY INC (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030018053-A1 | Substituted indolealkanoic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC. | 2003-01-23 | — | — | US | disclosed |
| WO-2001051489-A2 | METHODS FOR LOWERING URIC ACID LEVELS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018053-A1 | Substituted indolealkanoic acids | GPR119, AANAT, AADAT | AKR1A1 475/4885AKR1B1 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.