Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685494 | 0.98 | OPRM1 (0.44) | OPRM1PLA2G1BPLA2G2ASPHK1LMNA | |
| SCHEMBL8946581 | 0.86 | OPRM1 (0.42) | OPRM1PLA2G1BPLA2G2ASPHK1LMNA | |
| SCHEMBL13067518 | 0.86 | OPRM1 (0.42) | OPRM1PLA2G1BPLA2G2ASPHK1LMNA | |
| SCHEMBL6545348 | 0.85 | PLA2G1B (0.34) | PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL532756 | 0.84 | TSHR (0.30) | TSHR | |
| SCHEMBL28113967 | 0.78 | LMNA (0.41) | OPRM1PLA2G1BPLA2G2ALMNADNM1 | |
| SCHEMBL20219017 | 0.78 | LMNA (0.41) | OPRM1PLA2G1BPLA2G2ALMNADNM1 | |
| SCHEMBL11668627 | 0.78 | LMNA (0.41) | OPRM1PLA2G1BPLA2G2ALMNADNM1 | |
| SCHEMBL2839300 | 0.76 | LMNA (0.44) | PLA2G1BPLA2G2ASPHK1LMNADNM1 | |
| Hydrochloric Acid SCHEMBL8469058 | 0.76 | DNM1 (0.42) | OPRM1PLA2G1BPLA2G2ALMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268603-B1 | MANNICH BASES AND FURTHER COMPOUNDS BASED ON ALKYLDIPROPYLENETRIAMINES AS HARDENERS FOR EPOXY RESINS | VANTICO GMBH & CO KG (DE) | 2004-04-28 | — | — | EP | disclosed |
| US-6531567-B2 | Hardeners for epoxy resins | VANTICO GMBH & CO. (DE) | 2003-03-11 | — | — | US | disclosed |
| EP-1268603-A2 | MANNICH BASES AND FURTHER COMPOUNDS BASED ON ALKYLDIPROPYLENETRIAMINES AS HARDENERS FOR EPOXY RESINS | Vantico GmbH & Co. KG (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-20010034409-A1 | Mannich bases and further compounds based on alkyldipropylenetriamines | VANTICO GMBH & CO. KG | 2001-10-25 | — | — | US | disclosed |
| WO-2001072869-A2 | MANNICH BASES AND FURTHER COMPOUNDS BASED ON ALKYLDIPROPYLENETRIAMINES AS HARDENERS FOR EPOXY RESINS | VANTICO GMBH & CO. KG (DE) | 2001-10-04 | — | — | WO | disclosed |