Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298600 | 0.88 | POLB (0.42) | MAPTHTTTSHRMAPK1POLB | |
| SCHEMBL6299756 | 0.85 | POLB (0.44) | MAPTHTTTSHRMAPK1POLB | |
| SCHEMBL6298817 | 0.82 | ALDH1A1 (0.38) | MAPTHTTTSHRMAPK1POLB | |
| SCHEMBL6298803 | 0.80 | ALDH1A1 (0.41) | MAPTHTTTSHRMAPK1POLB | |
| SCHEMBL6992434 | 0.75 | ALDH1A1 (0.46) | MAPTHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4982717 | 0.70 | LMNA (0.48) | MAPTHTTMAPK1POLBALDH1A1 | |
| SCHEMBL9116925 | 0.70 | RAB9A (0.46) | MAPTHTTPOLBALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4984280 | 0.69 | LMNA (0.47) | MAPTHTTMAPK1POLBALDH1A1 | |
| SCHEMBL5961419 | 0.67 | ALDH1A1 (0.46) | MAPTHTTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6298823 | 0.67 | MAPT (0.59) | MAPTHTTMAPK1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413302-A2 | Substituted guanidines for the treatment of pain | Kadmus Pharmaceuticals, Inc. (US) | 2004-04-28 | — | — | EP | disclosed |