Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 4/20 | 0.49 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577799 | 0.97 | ALOX15 (0.57) | ALOX15TRPV1SIRT6CCR5NR1H4 | |
| SCHEMBL6581838 | 0.90 | NR1H4 (0.68) | NR1H4KMT2ANPC1RAB9A | |
| SCHEMBL6580317 | 0.89 | NR1H4 (0.67) | NR1H4KMT2APLK1NPC1RAB9A | |
| SCHEMBL6580185 | 0.89 | TRPV1 (0.61) | ALOX15TRPV1CCR5POLBPLK1 | |
| SCHEMBL6346820 | 0.85 | KMT2A (0.65) | ALOX15SIRT6NR1H4KMT2APOLB | |
| SCHEMBL6579889 | 0.84 | HDAC1 (0.62) | ALOX15TRPV1HDAC1POLBHDAC8 | |
| SCHEMBL6581908 | 0.83 | NPC1 (0.56) | ALOX15TRPV1SIRT6CCR5KMT2A | |
| SCHEMBL6580244 | 0.78 | NPC1 (0.64) | ALOX15CCR5KMT2APOLBNPC1 | |
| SCHEMBL6580500 | 0.78 | EPHX2 (0.57) | KMT2APOLBNPC1RAB9A | |
| SCHEMBL6577993 | 0.78 | PLK1 (0.61) | TRPV1HDAC1PLK1PLK3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |