Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752076 | 1.00 | NOS3 (0.44) | NOS3NOS1NOS2CNR2PDE2A | |
| SCHEMBL5751409 | 0.89 | ALDH1A1 (0.48) | NOS3NOS1NOS2CNR2PDE2A | |
| SCHEMBL5752379 | 0.89 | ALDH1A1 (0.48) | NOS3NOS1NOS2CNR2PDE2A | |
| SCHEMBL5755242 | 0.89 | NOS3 (0.46) | NOS3NOS1NOS2CNR2PDE2A | |
| SCHEMBL5752315 | 0.88 | CNR2 (0.45) | NOS3NOS1NOS2CNR2FPR2 | |
| SCHEMBL5753593 | 0.88 | FPR2 (0.46) | NOS3NOS1NOS2CNR2FPR2 | |
| SCHEMBL5753617 | 0.87 | FFAR2 (0.43) | CNR2FPR2PPARGPPARA | |
| SCHEMBL5752644 | 0.86 | NOS3 (0.42) | NOS3NOS1NOS2CNR2PDE2A | |
| SCHEMBL5751410 | 0.86 | NOS3 (0.47) | NOS3NOS1NOS2CNR2PDE2A | |
| SCHEMBL5751360 | 0.86 | NOS3 (0.42) | NOS3NOS1NOS2CNR2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | NOS3 2157/4885NOS1 1859/4885NOS2 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.