SCHEMBL658057

SCHEMBL658057

CCCOC(=O)C(C(C)C)C(C(=O)OCCC)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.40
ALDH1A1 P00352 4/20 0.39
LMNA P02545 1/20 0.38
ESR1 P03372 1/20 0.36
CHRM1 P11229 1/20 0.36
TSHR P16473 1/20 0.36
SLC6A2 P23975 1/20 0.36
KDR P35968 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPK1 P28482 1/20 0.33
ATM Q13315 1/20 0.33
GRM1 Q13255 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15015706 0.91 HCAR2 (0.39) HCAR2ALDH1A1LMNAESR1CHRM1
SCHEMBL234073 0.86 ALDH1A1 (0.54) HCAR2ALDH1A1LMNAESR1TSHR
SCHEMBL28340250 0.84 NAAA (0.52) HCAR2ALDH1A1LMNATSHRMAPK1
SCHEMBL29586743 0.82 HCAR2 (0.33) HCAR2LMNA
SCHEMBL6062574 0.80 HCAR2 (0.40) HCAR2ALDH1A1LMNAESR1CHRM1
SCHEMBL5007598 0.80 HCAR2 (0.45) HCAR2ALDH1A1LMNAESR1CHRM1
SCHEMBL12582839 0.80 HCAR2 (0.45) HCAR2ALDH1A1LMNAESR1CHRM1
SCHEMBL25387244 0.79 HCAR2 (0.43) HCAR2ALDH1A1LMNAESR1CHRM1
SCHEMBL101436 0.79
SCHEMBL4686450 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478863-B Catalyst component for olefin polymerization and preparation method thereof, catalyst and application thereof, and polyolefin and preparation method thereof 中国石油化工股份有限公司 2023-09-08 CN claimed
CN-114773506-A Catalyst for in-situ nucleation of polypropylene and preparation method and application thereof 山东京博石油化工有限公司 2022-07-22 CN claimed
CN-114478863-A Catalyst component for olefin polymerization, preparation method thereof, catalyst and application thereof, polyolefin and preparation method thereof 中国石油化工股份有限公司 2022-05-13 CN claimed
CN-111234075-A Catalyst for synthesizing alloy in polybutylene kettle, preparation method and application thereof 青岛科技大学 2020-06-05 CN claimed
US-20250188200-A1 CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN, AND PROPYLENE HOMOPOLYMER TOHO TITANIUM CO., LTD. (JP) 2025-06-12 US disclosed
US-20250101142-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN, AND POLYMER OF OLEFIN TOHO TITANIUM CO., LTD. (JP) 2025-03-27 US disclosed
EP-4491640-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, AND PROPYLENE HOMOPOLYMER TOHO TITANIUM CO., LTD. (JP) 2025-01-15 EP disclosed
EP-4491639-A1 SOLID CATALYST INGREDIENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING SOLID CATALYST INGREDIENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2025-01-15 EP disclosed
CN-118829663-A Catalyst for olefin polymerization, process for producing olefin polymer, and propylene homopolymer 东邦钛株式会社 2024-10-22 CN disclosed
CN-115515988-B Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2024-06-21 CN disclosed
WO-2024024880-A1 SOLID CATALYST COMPONENT MIXTURE FOR OLEFIN POLYMERIZATION, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING OLEFIN POLYMER 東邦チタニウム株式会社 2024-02-01 WO disclosed
WO-2023171435-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, AND PROPYLENE HOMOPOLYMER 東邦チタニウム株式会社 2023-09-14 WO disclosed
CN-114773506-A Catalyst for in-situ nucleation of polypropylene and preparation method and application thereof 山东京博石油化工有限公司 2022-07-22 CN disclosed
CN-114478863-A Catalyst component for olefin polymerization, preparation method thereof, catalyst and application thereof, polyolefin and preparation method thereof 中国石油化工股份有限公司 2022-05-13 CN disclosed
CN-111234075-A Catalyst for synthesizing alloy in polybutylene kettle, preparation method and application thereof 青岛科技大学 2020-06-05 CN disclosed
CN-111185241-A Metal catalyst and preparation method and application thereof 邯郸学院 2020-05-22 CN disclosed
EP-2399902-B1 PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANO SUCCINIC ACID DIESTERS CHINA PETROLEUM & CHEMICAL (CN) 2014-11-26 EP disclosed
US-8669392-B2 Process for preparing 2,3-di-non-straight-alkyl-2-cyanosuccinic acid diesters CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2014-03-11 US disclosed
US-20120046490-A1 PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANOSUCCINIC ACID DIESTERS CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-02-23 US disclosed
EP-2399902-A1 PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANO SUCCINIC ACID DIESTERS China Petroleum & Chemical Corporation (CN) 2011-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046490-A1 PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANOSUCCINIC ACID DIESTERS ACMSD, ADSL, CNDP2 HCAR2 45/4885ALDH1A1 1240/4885LMNA 479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.