Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | PLD1 | Q13393 | 6/20 | 0.46 |
| ▸ | PLD2 | O14939 | 3/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580649 | 0.79 | OPRM1 (0.62) | OPRM1OPRK1OPRL1OPRD1PLD1 | |
| SCHEMBL1838993 | 0.78 | OPRM1 (0.53) | OPRM1OPRK1OPRL1OPRD1PLD1 | |
| SCHEMBL6580272 | 0.78 | OPRM1 (0.66) | OPRM1OPRK1OPRL1OPRD1SLC18A3 | |
| SCHEMBL1837269 | 0.78 | OPRM1 (0.54) | OPRM1OPRK1OPRL1OPRD1PLD2 | |
| SCHEMBL1831981 | 0.77 | OPRM1 (0.58) | OPRM1PLD1PLD2ALDH1A1 | |
| SCHEMBL27804049 | 0.74 | ALDH1A1 (0.58) | OPRM1OPRK1OPRL1OPRD1PLD1 | |
| SCHEMBL27782364 | 0.74 | OPRM1 (0.58) | OPRM1OPRK1OPRL1OPRD1PLD1 | |
| SCHEMBL4679191 | 0.73 | OPRM1 (0.53) | OPRM1OPRK1OPRL1OPRD1PLD1 | |
| SCHEMBL22716722 | 0.72 | HSD11B1 (0.62) | OPRM1OPRK1OPRL1PLD1PLD2 | |
| SCHEMBL1833332 | 0.72 | HSD11B1 (0.68) | OPRM1OPRK1OPRL1SLC18A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-B9 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-18 | — | — | EP | claimed |
| EP-2160098-B1 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-11-10 | — | — | EP | claimed |