Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27751697 | 1.00 | HTR6 (0.61) | HTR6KCNH2HTR1ADRD2HTR2A | |
| SCHEMBL9147029 | 0.91 | HTR6 (0.56) | HTR6KCNH2 | |
| SCHEMBL9462735 | 0.91 | HTR6 (0.68) | HTR6KCNH2HTR1AHTR2AHTR7 | |
| SCHEMBL9150425 | 0.87 | HTR6 (0.55) | HTR6KCNH2HTR1AHTR2A | |
| SCHEMBL9462566 | 0.85 | HTR6 (0.56) | HTR6KCNH2HTR1A | |
| SCHEMBL10874677 | 0.83 | HTR6 (0.57) | HTR6HTR1AHTR2AHTR7 | |
| SCHEMBL7685212 | 0.82 | HTR6 (0.52) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL9463173 | 0.82 | HTR6 (0.61) | HTR6KCNH2HTR1AHTR2A | |
| SCHEMBL6583508 | 0.81 | HTR6 (0.54) | HTR6KCNH2HTR1A | |
| SCHEMBL9149499 | 0.80 | HTR6 (0.52) | HTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1243001-C | Process for the manufacture of sertindole | LUNDBECK & CO AS H (DK) | 2006-02-22 | — | — | CN | claimed |
| EP-1260511-B1 | Process for the preparation of 5-chloro-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydropyridin-4-yl)indole and method of manufacturing sertindole | LUNDBECK & CO AS H (DK) | 2004-12-29 | — | — | EP | claimed |
| EP-0983264-B1 | METHOD OF MANUFACTURING SERTINDOLE | LUNDBECK & CO AS H (DK) | 2004-02-04 | — | — | EP | claimed |
| EP-1260511-A1 | Process for the preparation of 5-chloro-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydropyridin-4-yl)indole and method of manufacturing sertindole | H. Lundbeck A/S (DK) | 2002-11-27 | — | — | EP | claimed |
| US-6335463-B1 | Method of manufacturing sertindole | H. LUNDBECK A/S (DK) | 2002-01-01 | — | — | US | claimed |
| CN-1261363-A | Process for the manufacture of sertindole | LUNDBECK & CO AS H (DK) | 2000-07-26 | — | — | CN | claimed |
| EP-0983264-A1 | METHOD OF MANUFACTURING SERTINDOLE | H. LUNDBECK A/S (DK) | 2000-03-08 | — | — | EP | claimed |
| WO-1998051685-A1 | METHOD OF MANUFACTURING SERTINDOLE | H. LUNDBECK A/S (DK) | 1998-11-19 | — | — | WO | claimed |
| CN-101899036-B | Method for preparing sertindole by using alkyl imidazole type ionic liquid as solvent | UNIV ZHENGZHOU | 2012-12-19 | — | — | CN | disclosed |
| CN-101899036-A | Method for preparing sertindole by using alkyl imidazole type ionic liquid as solvent | UNIV ZHENGZHOU | 2010-12-01 | — | — | CN | disclosed |
| CN-101362749-A | Sertindole synthesis method | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-02-11 | — | — | CN | disclosed |
| CN-1301963-C | Process for producing N-(4-fluobenzene radical)-N-(2-hydroxy-4-chlorobenzene group) glycocoll | LUNDBECK & CO AS H (DK) | 2007-02-28 | — | — | CN | disclosed |
| CN-1243001-C | Process for the manufacture of sertindole | LUNDBECK & CO AS H (DK) | 2006-02-22 | — | — | CN | disclosed |
| CN-1243001-C | Process for the manufacture of sertindole | LUNDBECK & CO AS H (DK) | 2006-02-22 | — | — | CN | disclosed |
| WO-1998051685-A1 | METHOD OF MANUFACTURING SERTINDOLE | H. LUNDBECK A/S (DK) | 1998-11-19 | — | — | WO | disclosed |
| WO-1998051685-A1 | METHOD OF MANUFACTURING SERTINDOLE | H. LUNDBECK A/S (DK) | 1998-11-19 | — | — | WO | disclosed |
| US-RE34299-E | Psychological disorders, neuroleptic agents, analgesics | H. LUNDBECK A/S (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0200322-B1 | HETEROCYCLIC COMPOUNDS | H. LUNDBECK A/S (DK) | 1990-02-28 | — | — | EP | disclosed |
| US-4710500-A | 1-(4'-fluorophenyl)-3,5-substituted indoles useful in the treatment of psychic disorders and pharmaceutical compositions thereof | H. LUNDBECK A/S (DK) | 1987-12-01 | — | — | US | disclosed |
| EP-0200322-A1 | Heterocyclic compounds | H. LUNDBECK A/S (DK) | 1986-11-05 | — | — | EP | disclosed |