Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | KHK | P50053 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462735 | 0.86 | HTR6 (0.68) | HTR6HTR2AKHKKCNH2HTR1A | |
| SCHEMBL10725470 | 0.82 | HTR6 (0.42) | HTR6KCNH2 | |
| Hydrochloric Acid SCHEMBL27751697 | 0.82 | HTR6 (0.61) | HTR6HTR2AKCNH2HTR1A | |
| SCHEMBL6580736 | 0.82 | HTR6 (0.61) | HTR6HTR2AKCNH2HTR1A | |
| SCHEMBL9462566 | 0.81 | HTR6 (0.56) | HTR6KCNH2HTR1ADRD3 | |
| SCHEMBL9462659 | 0.81 | SLC6A4 (0.55) | HTR6KCNH2 | |
| SCHEMBL17495361 | 0.81 | HTR6 (0.65) | HTR6HTR2AKHKHTR1A | |
| SCHEMBL10874677 | 0.79 | HTR6 (0.57) | HTR6HTR2AHTR1ADRD3 | |
| SCHEMBL9150425 | 0.78 | HTR6 (0.55) | HTR6HTR2AKHKKCNH2HTR1A | |
| SCHEMBL9150811 | 0.78 | HTR6 (0.60) | HTR6HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34299-E | Psychological disorders, neuroleptic agents, analgesics | H. LUNDBECK A/S (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0200322-B1 | HETEROCYCLIC COMPOUNDS | H. LUNDBECK A/S (DK) | 1990-02-28 | — | — | EP | disclosed |
| US-4710500-A | 1-(4'-fluorophenyl)-3,5-substituted indoles useful in the treatment of psychic disorders and pharmaceutical compositions thereof | H. LUNDBECK A/S (DK) | 1987-12-01 | — | — | US | disclosed |
| EP-0200322-A1 | Heterocyclic compounds | H. LUNDBECK A/S (DK) | 1986-11-05 | — | — | EP | disclosed |