SCHEMBL7685212

SCHEMBL7685212

Fc1ccccc1-n1cc(C2=CCNCC2)c2cc(Cl)ccc21

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 19/20 0.52
HTR1A P08908 2/20 0.49
DRD3 P35462 1/20 0.49
DRD2 P14416 1/20 0.47
HTR2A P28223 1/20 0.47
HTR7 P34969 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27751697 0.82 HTR6 (0.61) HTR6HTR1ADRD2HTR2AHTR7
SCHEMBL6580736 0.82 HTR6 (0.61) HTR6HTR1ADRD2HTR2AHTR7
SCHEMBL9147029 0.73 HTR6 (0.56) HTR6
SCHEMBL9462735 0.72 HTR6 (0.68) HTR6HTR1ADRD3HTR2AHTR7
SCHEMBL10874677 0.70 HTR6 (0.57) HTR6HTR1ADRD3HTR2AHTR7
SCHEMBL9150425 0.70 HTR6 (0.55) HTR6HTR1ADRD3HTR2A
SCHEMBL3210476 0.69 HTR6 (0.66) HTR6HTR1ADRD3HTR2AHTR7
SCHEMBL7864888 0.69 HTR6 (0.58) HTR6DRD3HTR2AHTR7
SCHEMBL6984515 0.69 HTR6 (0.64) HTR6HTR1ADRD3DRD2HTR2A
SCHEMBL11866031 0.69 HTR6 (1.00) HTR6HTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6335463-B1 Method of manufacturing sertindole H. LUNDBECK A/S (DK) 2002-01-01 US claimed