Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 7/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 6/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632729 | 0.86 | F2 (0.55) | GHSRF10PGRHTR6MAPT | |
| SCHEMBL7124112 | 0.80 | F2 (0.46) | GHSRF10HTR6MAPTF2 | |
| SCHEMBL5632002 | 0.77 | ALDH1A1 (0.49) | GHSRF10F2 | |
| SCHEMBL5632000 | 0.77 | ALDH1A1 (0.49) | GHSRF10F2 | |
| SCHEMBL5633771 | 0.76 | KMT2A (0.59) | GHSRF10PGRHTR6MAPT | |
| SCHEMBL5632397 | 0.74 | F10 (0.58) | F10F2 | |
| SCHEMBL5633181 | 0.73 | F10 (0.48) | F10CYP17A1F2 | |
| SCHEMBL5633179 | 0.73 | F10 (0.48) | F10CYP17A1F2 | |
| SCHEMBL7119023 | 0.72 | F10 (0.51) | F10F2 | |
| SCHEMBL8546329 | 0.71 | F2 (0.73) | BRAFPGRCYP17A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880502-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ASTRAZENECA AB (SE) | 2004-09-01 | — | — | EP | claimed |