SCHEMBL7119023

SCHEMBL7119023

CC(C)(C)OC(=O)Nc1cccc(OC2CCN(c3ccncc3)CC2)c1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.51
F2 P00734 4/20 0.49
ELANE P08246 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7112229 0.88 F10 (0.49) F10
SCHEMBL5632397 0.85 F10 (0.58) F10F2ELANE
SCHEMBL2951356 0.75 LNPEP (0.48) F10
SCHEMBL23213657 0.75 USP30 (0.50)
SCHEMBL29796156 0.75 USP30 (0.50)
SCHEMBL10260514 0.74 HTR1F (0.52) F2
SCHEMBL1456142 0.73 CKS1B (0.54)
SCHEMBL5632535 0.73 F10 (0.49) F10F2ELANE
Hydrochloric Acid SCHEMBL4504668 0.73 HTR1F (0.51) F2
SCHEMBL6580787 0.72 GHSR (0.48) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030207882-A1 Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents ZENECA LIMITED 2003-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207882-A1 Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents F2, SERPINC1, F11 F10 8/4885F2 1/4885ELANE 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.