SCHEMBL6580919

SCHEMBL6580919

C=CCN(CC=C)c1ccc(N)c(C)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.62
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
TSHR P16473 1/20 0.41
CRHR1 P34998 2/20 0.38
SKP2 Q13309 1/20 0.36
APAF1 O14727 1/20 0.36
CHKA P35790 1/20 0.34
ESR1 P03372 2/20 0.33
AR P10275 1/20 0.33
ESR2 Q92731 1/20 0.33
PTPN1 P18031 1/20 0.33
DHFR P00374 1/20 0.33
UTS2R Q9UKP6 1/20 0.33
GAA P10253 1/20 0.32
RAD52 P43351 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9153229 0.92 S100B (0.72) S100BALDH1A1CYP3A4TDP1TSHR
SCHEMBL8524528 0.80 ALDH1A1 (0.42) S100BALDH1A1CRHR1CHKAPTPN1
SCHEMBL23066756 0.79 CRHR1 (0.46) S100BALDH1A1TDP1CRHR1CHKA
SCHEMBL29350181 0.77 S100B (1.00) S100BALDH1A1CYP3A4TDP1TSHR
SCHEMBL34104 0.77 S100B (1.00) S100BALDH1A1CYP3A4TDP1TSHR
SCHEMBL11142526 0.76 ALDH1A1 (0.43) S100BALDH1A1TSHRCRHR1CHKA
Hydrochloric Acid SCHEMBL3385174 0.76 S100B (0.96) S100BALDH1A1CYP3A4TDP1TSHR
Hydrochloric Acid SCHEMBL2136137 0.76 S100B (0.96) S100BALDH1A1CYP3A4TDP1TSHR
SCHEMBL11037811 0.75 CHKA (0.34) S100BALDH1A1CRHR1CHKAPTPN1
SCHEMBL11579110 0.75 S100B (0.86) S100BALDH1A1CYP3A4TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194812-B1 Process for preparing a color developer composition EASTMAN CHEM CO (US) 2004-05-06 EP disclosed
EP-1194812-A1 STABILIZED PHENYLENEDIAMINE COLOR DEVELOPER COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2002-04-10 EP disclosed
WO-2000077574-A1 STABILIZED PHENYLENEDIAMINE COLOR DEVELOPER COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2000-12-21 WO disclosed
US-6130029-A Stabilized phenylenediamine color developer compositions EASTMAN CHEMICAL COMPANY (US) 2000-10-10 US disclosed