Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205126 | 0.93 | L3MBTL1 (0.60) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6325847 | 0.91 | MAPT (0.64) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9786970 | 0.91 | MAPT (0.74) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL27628199 | 0.90 | MAPT (0.73) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9786937 | 0.88 | NR4A2 (0.66) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1068092 | 0.87 | MAPT (0.69) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL8136104 | 0.85 | MAPT (0.67) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| Methane SCHEMBL28765047 | 0.85 | MAPT (0.67) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9368178 | 0.85 | RAB9A (0.52) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3868073 | 0.84 | MAPT (0.63) | MAPTNPC1RAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836497-B1 | CATALYST COMPOUNDS | UNIV LIVERPOOL (GB) | 2016-03-23 | — | — | EP | disclosed |
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| WO-2013153407-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
| US-8012901-B1 | Method of synthesizing enantiopure mexiletine analogues and novel β-thiophenoxy and pyridyl ethers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-06 | — | — | US | disclosed |
| US-4957934-A | AROMATASE INHIBITORS, TREATMENT OF STEROID HORMONE DEPENDENT DISEASES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-09-18 | — | — | US | disclosed |
| CN-1008735-B | Pyrrole ylmethyl-cyclopropyl-carbinol derivatives with replacement is a composition of active components | BAYER AG (DE) | 1990-07-11 | — | — | CN | disclosed |
| US-4921528-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| CN-85108725-A | The preparation method and the application thereof of the pyrroles's methyl-cyclopropyl-carbinol derivatives that replaces | — | 1986-05-10 | — | — | CN | disclosed |
| EP-0180136-A2 | Substituted azolylmethyl-cyclopropyl carbinol derivatives | BAYER AG (DE) | 1986-05-07 | — | — | EP | disclosed |
| US-4212865-A | BACTERICIDES | RIKER LABORATORIES, INC. (US) | 1980-07-15 | — | — | US | disclosed |
| US-4190590-A | DISINFECTING AND STERILIZING DENTAL AND MEDICAL EQUIPMENT | RIKER LABORATORIES, INC. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4124602-A | OPTIONALLY SUBSTITUTED 3-(CYANOPHENYL)BENZOFURANS | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4048323-A | Antimicrobial (2-nitro-3-benzofuranyl)-benzoic acids | RIKER LABORATORIES, INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-3952002-A | FUNGICIDE, MICROBIOCIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | MAPT 964/4885NPC1 2687/4885RAB9A 2902/4885 |
| US-20150080592-A1 | CATALYST COMPOUNDS | IDH3B, IDH2, NQO1 | MAPT 4290/4885NPC1 2868/4885RAB9A 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.