Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577070 | 0.89 | GPR17 (0.48) | MAPTGPR17HSD17B10TSHRMEN1 | |
| SCHEMBL6578984 | 0.89 | GPR84 (0.39) | HTTMAPTGPR17SMN1; SMN2HSD17B10 | |
| SCHEMBL6579789 | 0.88 | PTGES (0.43) | HTTGPR17SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6582134 | 0.81 | PARP1 (0.44) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14979853 | 0.71 | MAPT (0.46) | HTTMAPTSMN1; SMN2HSD17B10TSHR | |
| SCHEMBL7988816 | 0.69 | PARP1 (0.47) | MAPTGPR17TSHRALDH1A1MEN1 | |
| SCHEMBL7988879 | 0.69 | PARP1 (0.47) | MAPTGPR17TSHRALDH1A1MEN1 | |
| SCHEMBL7988069 | 0.68 | PARP1 (0.43) | MAPTGPR17SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8000822 | 0.68 | PARP1 (0.43) | MAPTGPR17SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8001710 | 0.68 | GSK3B (0.43) | MAPTHSD17B10TSHRALDH1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |