Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381862 | 0.79 | POLB (0.56) | KDM4EALDH1A1HTTMAPTMEN1 | |
| SCHEMBL27399106 | 0.78 | TSHR (0.59) | LMNAKDM4EALDH1A1L3MBTL1HTT | |
| SCHEMBL8971238 | 0.78 | ALDH1A1 (0.73) | BCL2LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6581654 | 0.78 | KDM4E (0.54) | BCL2LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6582831 | 0.78 | ALDH1A1 (0.78) | LMNASMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1044513 | 0.78 | TSHR (0.58) | LMNASMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6577993 | 0.77 | PLK1 (0.61) | — | |
| SCHEMBL6581823 | 0.77 | PLK1 (0.58) | LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6582660 | 0.76 | KDM4E (0.63) | LMNASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL6580460 | 0.75 | NPC1 (0.48) | SMN1; SMN2KDM4EALDH1A1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |