Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876977 | 0.70 | THRB (0.36) | THRBLMNA | |
| SCHEMBL27700346 | 0.69 | THRB (0.40) | THRBLMNA | |
| SCHEMBL1162241 | 0.67 | THRB (0.38) | THRBLMNA | |
| SCHEMBL440377 | 0.67 | THRB (0.38) | THRBLMNA | |
| SCHEMBL271779 | 0.67 | THRB (0.38) | THRBLMNA | |
| SCHEMBL873737 | 0.65 | THRB (0.36) | THRBLMNA | |
| SCHEMBL11451477 | 0.65 | THRB (0.36) | THRBLMNA | |
| SCHEMBL3822689 | 0.65 | THRB (0.36) | THRBLMNA | |
| SCHEMBL873736 | 0.65 | THRB (0.36) | THRBLMNA | |
| SCHEMBL27678912 | 0.65 | LMNA (0.41) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438291-A1 | ARALKYL-TETRAHYDRO-PYRIDINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003033466-A1 | ARALKYL-TETRAHYDRO-PYRIDINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2003-04-24 | — | — | WO | disclosed |