SCHEMBL873736

SCHEMBL873736

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nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.35
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873737 1.00 THRB (0.36) THRBLMNAGRIK1GRIK2
SCHEMBL13480690 0.85 TRPA1 (0.35) THRBLMNA
SCHEMBL21225089 0.80 THRB (0.33) THRBLMNA
SCHEMBL13876977 0.79 THRB (0.36) THRBLMNA
SCHEMBL8741345 0.78 LPAR2 (0.32)
SCHEMBL8643775 0.78 LPAR2 (0.32)
SCHEMBL8741353 0.78 LPAR2 (0.32)
SCHEMBL20533472 0.77 THRB (0.35) THRBLMNA
SCHEMBL11539456 0.76 HTT (0.33) GRIK1GRIK2
SCHEMBL11539460 0.76 HTT (0.33) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12496370-B2 Freshening compositions comprising controlled release modulators Arylessence, Inc. (US) 2025-12-16 US claimed
US-11806448-B2 Freshening compositions comprising controlled release modulators Arylessence, Inc. (US) 2023-11-07 US claimed
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
US-20260069734-A1 FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS ARYLESSENCE INC (US) 2026-03-12 US disclosed
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS PBC (US) 2026-01-29 US disclosed
US-12496370-B2 Freshening compositions comprising controlled release modulators Arylessence, Inc. (US) 2025-12-16 US disclosed
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS, PBC 2025-10-09 US disclosed
US-12378358-B2 Resin composition, molded body, and their application MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-08-05 US disclosed
US-20250236810-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING BENZENE DERIVATIVES OSMO LABS, PBC 2025-07-24 US disclosed
US-20250234910-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES OSMO LABS, PBC 2025-07-24 US disclosed
WO-2025070466-A1 SEAMLESS CAPSULE FOR ORAL CAVITY 森下仁丹株式会社 2025-04-03 WO disclosed
EP-1827370-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR Showa Denko K.K. (JP) 2007-09-05 EP disclosed
US-20070092623-A1 Food products containing a fruit component TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-04-26 US disclosed
EP-1689256-A1 FOOD PRODUCTS CONTAINING A FRUIT COMPONENT Takasago International Corporation (JP) 2006-08-16 EP disclosed
US-20060165622-A1 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-07-27 US disclosed
WO-2006068276-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR SHOWA DENKO K.K. (JP) 2006-06-29 WO disclosed
EP-1561476-A1 DEODORANT COMPOSITION Takasago International Corporation (JP) 2005-08-10 EP disclosed
WO-2005048743-A1 FOOD PRODUCTS CONTAINING A FRUIT COMPONENT TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-06-02 WO disclosed
US-5739100-A Cis-3-hexenal-cis-3-hexenyl acetal compound, process for preparing same, and fragrance-or flavor-imparting or fragrance-or flavor-retaining agent and perfume composition containing same NIPPON ZEON CO., LTD. (JP) 1998-04-14 US disclosed
EP-0738700-A1 CIS-3-HEXENAL CIS-3-HEXENYL ACETAL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND FLAVOR/TASTE IMPARTING AGENT, FLAVOR/TASTE RETAINING AGENT AND PERFUME COMPOSITION EACH CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 1996-10-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CYP8B1, CYP1B1, BBOX1 THRB 1397/4885LMNA 2153/4885GRIK1 1264/4885
US-20250236810-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING BENZENE DERIVATIVES BBOX1, NISCH, TAS2R4 THRB 2031/4885LMNA 2640/4885GRIK1 4070/4885
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES TAS2R42, TAS2R4, TAS2R41 THRB 2294/4885LMNA 1935/4885GRIK1 3784/4885
US-20260069734-A1 FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS FFAR1, FFAR2, FFAR3 THRB 2433/4885LMNA 399/4885GRIK1 2016/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 THRB 1512/4885LMNA 2153/4885GRIK1 1453/4885
US-20250234910-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES TAS1R3, TAS2R5, TRPA1 THRB 616/4885LMNA 3115/4885GRIK1 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.