Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.40 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.40 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184603 | 0.75 | ALOX5 (0.52) | MAOB | |
| SCHEMBL6582613 | 0.74 | SIGMAR1 (0.49) | — | |
| SCHEMBL11171006 | 0.71 | PPARD (0.47) | PPARDPPARAKMT2AMEN1KCNH2 | |
| SCHEMBL202923 | 0.70 | PARP1 (0.63) | SLC2A1SLC2A4SLC2A8KMT2ASMPD1 | |
| SCHEMBL24041762 | 0.69 | BCHE (0.50) | SLC2A1SLC2A4SLC2A8KCNH2FFAR1 | |
| SCHEMBL5784919 | 0.68 | MAOB (0.58) | PPARDPPARAKCNH2MAOB | |
| SCHEMBL13439834 | 0.67 | NPC1 (0.58) | SMPD1MAOB | |
| SCHEMBL958012 | 0.67 | CYP19A1 (0.41) | KMT2AMEN1KCNH2 | |
| SCHEMBL791296 | 0.66 | MAOB (0.69) | MAOB | |
| SCHEMBL13815894 | 0.66 | KIF11 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |