Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.49 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582968 | 0.83 | CASP1 (0.45) | — | |
| SCHEMBL6584387 | 0.82 | CASP1 (0.57) | — | |
| SCHEMBL6585217 | 0.78 | CASP1 (0.45) | — | |
| SCHEMBL8730444 | 0.76 | SIGMAR1 (0.63) | SIGMAR1EBPTMEM97 | |
| SCHEMBL6584961 | 0.76 | PDE4B (0.44) | — | |
| SCHEMBL6582616 | 0.74 | PPARD (0.40) | — | |
| SCHEMBL6585141 | 0.74 | PDE4B (0.47) | — | |
| SCHEMBL6582744 | 0.73 | SIGMAR1 (0.50) | SIGMAR1EBPTMEM97 | |
| SCHEMBL6587626 | 0.71 | PDE4B (0.48) | — | |
| SCHEMBL6583889 | 0.71 | PDE4A (0.60) | SIGMAR1EBPTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |