Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.56 |
| ▸ | SELP | P16109 | 1/20 | 0.55 |
| ▸ | SELE | P16581 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580165 | 0.90 | KDM4E (0.53) | KDM4EPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6582831 | 0.86 | ALDH1A1 (0.78) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL10497116 | 0.79 | HCAR2 (0.78) | KDM4ESMN1; SMN2RAB9ANPC1HCAR2 | |
| SCHEMBL3378244 | 0.79 | ALDH1A1 (0.51) | KDM4EPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6577993 | 0.79 | PLK1 (0.61) | — | |
| SCHEMBL6581823 | 0.79 | PLK1 (0.58) | KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6579983 | 0.78 | CETP (0.57) | LMNATSHRKMT2AMAPK1 | |
| SCHEMBL6580152 | 0.78 | CETP (0.57) | LMNATSHRKMT2AMAPK1 | |
| SCHEMBL7108471 | 0.77 | KDM4E (1.00) | KDM4EPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8440269 | 0.76 | POLB (0.80) | KDM4EPOLBALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |