Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.51 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582831 | 0.81 | ALDH1A1 (0.78) | KDM4ELMNASMN1; SMN2ALDH1A1KCNQ2 | |
| SCHEMBL6577393 | 0.80 | ALDH1A1 (0.60) | KDM4ELMNASMN1; SMN2ALDH1A1KCNQ2 | |
| SCHEMBL8636686 | 0.79 | MAPK8 (0.67) | KDM4ELMNASMN1; SMN2ALDH1A1KCNQ2 | |
| SCHEMBL28600470 | 0.79 | KMT2A (0.66) | KDM4ELMNASMN1; SMN2ALDH1A1KCNQ2 | |
| SCHEMBL8632192 | 0.79 | KCNQ2 (0.58) | KDM4ELMNASMN1; SMN2ALDH1A1KCNQ2 | |
| SCHEMBL7724422 | 0.79 | MAPT (0.62) | LMNAALDH1A1KCNQ2PARP14KCNJ5 | |
| SCHEMBL28600464 | 0.78 | MAPK10 (0.68) | KDM4ESMN1; SMN2ALDH1A1KCNQ2MAPK8 | |
| SCHEMBL28618234 | 0.78 | ALDH1A1 (0.54) | KDM4ELMNASMN1; SMN2ALDH1A1KCNQ2 | |
| SCHEMBL6581781 | 0.78 | KCNQ2 (0.60) | KDM4ELMNASMN1; SMN2ALDH1A1KCNQ2 | |
| SCHEMBL3378244 | 0.77 | ALDH1A1 (0.51) | KDM4ELMNASMN1; SMN2ALDH1A1PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |