Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369263 | 0.80 | GAA (0.50) | NR3C1GAACYP2D6TSHRSIGMAR1 | |
| SCHEMBL6582036 | 0.77 | NR3C1 (0.47) | NR3C1GAACYP2D6ALDH1A1TSHR | |
| SCHEMBL28026914 | 0.75 | GAA (0.46) | NR3C1GAACYP2D6TSHRCYP3A4 | |
| Methane SCHEMBL726862 | 0.75 | NR3C1 (0.48) | NR3C1GAACYP2D6ALDH1A1TSHR | |
| SCHEMBL653269 | 0.74 | GAA (0.57) | NR3C1GAACYP2D6TSHRSIGMAR1 | |
| SCHEMBL4562285 | 0.74 | NR3C1 (0.44) | NR3C1GAASIGMAR1MGLLMEN1 | |
| SCHEMBL14498561 | 0.72 | GAA (0.43) | NR3C1GAACYP2D6TSHRSIGMAR1 | |
| SCHEMBL19618751 | 0.71 | OPRL1 (0.52) | CYP2D6ALDH1A1TSHRCYP3A4SIGMAR1 | |
| SCHEMBL3315042 | 0.71 | NR3C1 (0.49) | NR3C1GAACYP2D6CYP3A4SIGMAR1 | |
| SCHEMBL13090069 | 0.71 | NR3C1 (0.52) | NR3C1GAACYP2D6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |