Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583875 | 0.92 | PPARG (0.49) | FFAR1KDRPPARGMAPTPPARA | |
| SCHEMBL4038141 | 0.84 | KDR (0.67) | FFAR1KDRPPARGMAPTPPARA | |
| SCHEMBL1731684 | 0.84 | KDR (0.53) | FFAR1KDRPPARGMAPTPPARA | |
| SCHEMBL4843985 | 0.84 | FFAR1 (0.59) | FFAR1KDRPPARGMAPTPPARA | |
| SCHEMBL6157314 | 0.83 | ALDH1A1 (0.54) | FFAR1KDRPPARGMAPTPPARA | |
| SCHEMBL6583779 | 0.83 | KDR (0.53) | FFAR1KDRPPARGMAPTPPARA | |
| SCHEMBL12617575 | 0.82 | KDR (0.71) | FFAR1KDRPPARGPPARA | |
| SCHEMBL4038108 | 0.82 | MAPT (0.45) | FFAR1KDRPPARGMAPTPPARA | |
| SCHEMBL6582673 | 0.82 | FFAR1 (0.49) | FFAR1KDRPPARGMAPTPPARA | |
| SCHEMBL6583241 | 0.81 | TRPA1 (0.48) | FFAR1KDRPPARGMAPTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |