Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589980 | 0.85 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7239484 | 0.84 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1MAPK1NPC1SMN1; SMN2 | |
| SCHEMBL1313733 | 0.84 | L3MBTL1 (0.74) | L3MBTL1ALDH1A1MAPK1NPC1SMN1; SMN2 | |
| SCHEMBL29173176 | 0.83 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1MAPK1NPC1SMN1; SMN2 | |
| SCHEMBL6472886 | 0.82 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1MAPK1NPC1SMN1; SMN2 | |
| SCHEMBL6043936 | 0.81 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1MAPK1NPC1SMN1; SMN2 | |
| SCHEMBL311599 | 0.80 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1MAPK1NPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11672178 | 0.80 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNAPOLBSCN1A | |
| SCHEMBL6587986 | 0.78 | HTT (0.56) | ALDH1A1MAPK1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL11109763 | 0.78 | BCHE (0.54) | MAPTHTTLMNASCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |
| EP-1177178-A1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068206-A1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |