Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583837 | 0.85 | L3MBTL1 (0.55) | ALDH1A1LMNASCN1ASCN2ASCN3A | |
| SCHEMBL1671161 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4ELMNANAPRTL3MBTL1 | |
| SCHEMBL3084388 | 0.81 | L3MBTL1 (0.50) | ALDH1A1KDM4ELMNANAPRTL3MBTL1 | |
| SCHEMBL11109763 | 0.81 | BCHE (0.54) | KDM4ELMNASCN1ASCN2ASCN3A | |
| SCHEMBL123523 | 0.81 | L3MBTL1 (0.64) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL6160250 | 0.80 | PTPN1 (0.55) | ALDH1A1KDM4ELMNAL3MBTL1TDP1 | |
| SCHEMBL3083328 | 0.79 | NAPRT (0.49) | ALDH1A1KDM4ELMNASCN1ASCN2A | |
| SCHEMBL11338177 | 0.79 | ALDH1A1 (0.76) | ALDH1A1KDM4ELMNASCN1ASCN2A | |
| SCHEMBL11451808 | 0.79 | PTPN1 (0.57) | ALDH1A1KDM4ELMNAL3MBTL1TDP1 | |
| SCHEMBL1505205 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4ELMNANAPRTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |