Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578118 | 0.86 | CTSK (0.51) | CTSKCTSLCASP1CASP3CAPN1 | |
| SCHEMBL6577961 | 0.86 | CTSK (0.51) | CTSKCTSLTAOK1TAOK3CTSS | |
| SCHEMBL6583598 | 0.85 | CTSL (0.51) | CTSKCTSLCASP1CASP3CAPN1 | |
| SCHEMBL6580234 | 0.81 | CTSL (0.49) | CTSKCTSLCASP1CASP3CAPN1 | |
| SCHEMBL6580295 | 0.80 | CTSK (0.60) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6577721 | 0.79 | CTSL (0.47) | CTSKCTSLCASP1CASP3CAPN1 | |
| SCHEMBL6578042 | 0.79 | CTSK (0.54) | CTSKCTSLCASP1CASP3CAPN1 | |
| SCHEMBL6580001 | 0.79 | CTSL (0.48) | CTSKCTSLCASP1CASP3CAPN1 | |
| SCHEMBL7379929 | 0.77 | CTSK (0.55) | CTSKCTSLTAOK1TAOK3CTSS | |
| SCHEMBL6578074 | 0.77 | CTSK (0.49) | CTSKCASP1CASP3CAPN1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |