SCHEMBL6584237

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3322385	0.85	ALDH1A1 (0.59)	TSHRTDP1ALDH1A1CYP3A4RECQL
	SCHEMBL30459805	0.85	ALDH1A1 (0.59)	TSHRTDP1ALDH1A1CYP3A4RECQL
	Hydrochloric Acid SCHEMBL27467893	0.84	ALDH1A1 (0.58)	TSHRTDP1ALDH1A1CYP3A4RECQL
	SCHEMBL5341171	0.82	ALDH1A1 (0.50)	TSHRTDP1ALDH1A1CYP3A4RECQL
	SCHEMBL28322481	0.81	TDP1 (0.58)	TSHRTDP1ALDH1A1CYP3A4RECQL
	SCHEMBL7811895	0.81	MAPT (0.57)	TSHRTDP1ALDH1A1CYP3A4RECQL
	SCHEMBL6437317	0.80	NPSR1 (0.52)	TSHRTDP1ALDH1A1CYP3A4RECQL
	SCHEMBL8616062	0.79	MAPT (0.55)	TSHRTDP1ALDH1A1CYP3A4RECQL
	SCHEMBL978709	0.79	TSHR (0.62)	TSHRTDP1ALDH1A1CYP3A4RECQL
	SCHEMBL11554160	0.79	MAPT (0.56)	TSHRTDP1ALDH1A1RECQLMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.