Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586658 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAPTPPARGPPARAMEN1 | |
| SCHEMBL6586838 | 0.90 | KDM4E (0.46) | ALDH1A1KDM4EMAPTRXFP1TACR2 | |
| SCHEMBL6582331 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EMAPTPPARAKMT2A | |
| SCHEMBL6582336 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EMAPTPPARAKMT2A | |
| SCHEMBL6582227 | 0.80 | TRPA1 (0.48) | ALDH1A1KDM4EMAPTPPARGPPARA | |
| SCHEMBL6582223 | 0.80 | TRPA1 (0.48) | ALDH1A1KDM4EMAPTPPARGPPARA | |
| SCHEMBL5372453 | 0.80 | KDR (0.48) | ALDH1A1KDM4EMAPTRXFP1TACR2 | |
| SCHEMBL4747663 | 0.79 | FFAR1 (0.63) | ALDH1A1KDM4EMAPTPPARGPPARA | |
| SCHEMBL4748219 | 0.78 | MAOA (0.56) | PPARGPPARAFFAR1NPC1RAB9A | |
| SCHEMBL6584022 | 0.78 | FDPS (0.59) | ALDH1A1KDM4EMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |