Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.40 |
| ▸ | HTR2A | P28223 | 16/20 | 0.40 |
| ▸ | DRD3 | P35462 | 16/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22410924 | 0.83 | HTR1A (0.42) | DRD2HTR2ADRD3 | |
| SCHEMBL6582204 | 0.83 | HTR1A (0.42) | DRD2HTR2ADRD3 | |
| SCHEMBL6585844 | 0.79 | TRPV1 (0.36) | DRD2HTR2ADRD3MTNR1AMTNR1B | |
| SCHEMBL6581590 | 0.77 | HTR1A (0.50) | DRD2HTR2ADRD3 | |
| SCHEMBL6583942 | 0.75 | NOTUM (0.36) | DRD2HTR2ADRD3MTNR1AMTNR1B | |
| SCHEMBL6583915 | 0.74 | HTR1A (0.45) | DRD2HTR2A | |
| SCHEMBL6581720 | 0.69 | HTR1A (0.49) | — | |
| SCHEMBL6583413 | 0.69 | ADRB1 (0.50) | — | |
| SCHEMBL8485654 | 0.67 | POLB (0.36) | DRD2 | |
| SCHEMBL7480063 | 0.67 | HTR1A (0.50) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861837-B1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2004-04-28 | — | — | EP | disclosed |
| US-5968954-A | EXHIBIT SELECTIVE BINDING AFFINITY FOR 5-HYDROXYTRYPTAMINE RECEPTORS | ADIR ET COMPAGNIE (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0861837-A1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-02 | — | — | EP | disclosed |