Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403405 | 0.90 | KDM4E (0.54) | GPR119KDM4EPKM | |
| SCHEMBL20937163 | 0.86 | NR1H2 (0.49) | GPR119 | |
| SCHEMBL20937171 | 0.86 | NR1H2 (0.49) | GPR119 | |
| SCHEMBL29501493 | 0.86 | NR1H2 (0.49) | GPR119 | |
| SCHEMBL23545068 | 0.86 | NR1H2 (0.49) | GPR119 | |
| SCHEMBL22797037 | 0.83 | PTPN2 (0.62) | — | |
| SCHEMBL22797244 | 0.82 | ALDH1A1 (0.58) | GPR119 | |
| SCHEMBL6583545 | 0.82 | FAAH (0.50) | GPR119KDM4EPKM | |
| SCHEMBL23558620 | 0.81 | NAMPT (0.53) | GPR119KDM4EPKM | |
| SCHEMBL22398002 | 0.81 | USP30 (0.38) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455788-A1 | 1-GLYCINYL-4-AMINOMETHYL-PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003049737-A1 | CHEMICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |