Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585901 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| SCHEMBL6587522 | 0.83 | EPHX1 (0.53) | ALDH1A1HPGDGAASMN1; SMN2POLB | |
| SCHEMBL6585742 | 0.83 | EPHX1 (0.53) | ALDH1A1HPGDGAASMN1; SMN2POLB | |
| SCHEMBL6587301 | 0.82 | LPAR1 (0.49) | ALDH1A1TDP1GAASMN1; SMN2POLB | |
| SCHEMBL6587300 | 0.82 | LPAR1 (0.49) | ALDH1A1TDP1GAASMN1; SMN2POLB | |
| SCHEMBL6640602 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| SCHEMBL6587549 | 0.78 | ALDH1A1 (0.68) | ALDH1A1GAASMN1; SMN2GLAMAPT | |
| SCHEMBL6587541 | 0.78 | ALDH1A1 (0.68) | ALDH1A1GAASMN1; SMN2GLAMAPT | |
| SCHEMBL6587537 | 0.78 | ALDH1A1 (0.68) | ALDH1A1GAASMN1; SMN2GLAMAPT | |
| SCHEMBL6587736 | 0.75 | MEN1 (0.57) | ALDH1A1TDP1TSHRGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |