Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586310 | 1.00 | ACLY (0.40) | ACLYKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6587878 | 0.79 | LMNA (0.49) | ACLYKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6587872 | 0.79 | LMNA (0.49) | ACLYKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10873618 | 0.75 | EGFR (0.51) | ALDH1A1HPGDHTTKDM4EL3MBTL1 | |
| SCHEMBL11643310 | 0.75 | SMN1; SMN2 (0.41) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL10873613 | 0.75 | EGFR (0.51) | ALDH1A1HPGDHTTKDM4EL3MBTL1 | |
| SCHEMBL6080333 | 0.74 | LMNA (0.52) | ACLYKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10876160 | 0.71 | MEN1 (0.49) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10876148 | 0.71 | MEN1 (0.49) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10876517 | 0.70 | MAPK1 (0.55) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |